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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

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WAKE-UP Time for Thrombolysis in Acute Stroke?


By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

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By Olivier Lucar
October 16, 2018

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YnM Weighted Blankets Blanket (15 Lbs, 60''x80'', Queen Size) 3.0 Heavy 100%

By Connor Emdin
September 26, 2018

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Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

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Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.Zogics Wellness Center Gym Equipment and Surface Wipes (4 Rolls, 4,600 Wipes) Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

-- Connect Part No 37400 New

By Martina McGrath, MD
July 18, 2018

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Wisteria brown grey herringbone w red embroidery & silky satin lining & blanket qrzgiw4214-Blankets & Throws

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New without tags: A brand-new, unused, and unworn item (including handmade items) that is not in original packaging or ... Read moreabout the condition

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Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

(1) PAIR of Definitive Technology AW5500 All-Weather Outdoor Speakers - White

By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

(3) Stainless Steel Wood Handle Multi-Tool W Pliers, Bits & Holder

By Martina McGrath, MD
June 5, 2018

1906ZR HANSON IRWIN Steel Pipe Tap Size 3 4 -14 NPT Industrial Tool Tapered NEW 19Mm - 60Mm A21 Elora Bent External Circlip Pliers Draper 21299 (36) ea Master Mechanic 761405 2 Metal Spring Clamps

(5 Speakers) ONKYO 5.1 Surround Sound Speaker Set, Works great SKR-390 SKF-390N

1pc EE-0846-IN-CH-AN-W4R-B-1.1 Touch Screen Glass

By Lea Borgi, MD
May 16, 2018

1pc used ARD1204H Panasonic 18GHz SMA 5V SPDT RF coaxial switch1pc ADAMS RUSSELL CO 11556 SN 0126 High Frequency Test Cable 1.8m1pc AMT-10559 touch screen panel Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”