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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

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WAKE-UP Time for Thrombolysis in Acute Stroke?

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By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

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By Olivier Lucar
October 16, 2018

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Shark Motorized Floor Nozzle Brush for Model NV22L Part Number 1135FC

By Connor Emdin
September 26, 2018

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Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

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Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.Shark redator Bagless Vacuum Cleaner W Attachments Model NV500W31 58548-1 Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

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By Martina McGrath, MD
July 18, 2018

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New: A brand-new, unused, unopened, undamaged item in its original packaging (where packaging is ... Read moreabout the condition






Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

Shop-Vac 5895400 4.5-Peak Horsepower AllAround EZ Series Wet Dry Vacuum,

By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

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By Martina McGrath, MD
June 5, 2018

Twist Slow Close No Rust Stainless Steel Pedal Bin - 5LUmbra SKINNY CAN White 2082610-661 Silhouettone work station (heavy duty)

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Upright Carpet Vacuum Cleaner Home Powerful Deep Clean Pet Bissell Bagless, NEW

By Lea Borgi, MD
May 16, 2018

USPS Aiibot Convenient Smart Vacuum Cleaner Sweeping Robot Three Cleaning ModesVacmaster 12 Gallon, 5 Peak HP, Wet Dry Vacuum with Detachable Blower, VBV1210Vacmaster HEPA Cartridge Filter VKHF001---New Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”